Cargando…

Renal Inflammation and Innate Immune Activation Underlie the Transition From Gentamicin-Induced Acute Kidney Injury to Renal Fibrosis

Subjects recovering from acute kidney injury (AKI) are at risk of developing chronic kidney disease (CKD). The mechanisms underlying this transition are unclear and may involve sustained activation of renal innate immunity, with resulting renal inflammation and fibrosis. We investigated whether the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Albino, Amanda Helen, Zambom, Fernanda Florencia Fregnan, Foresto-Neto, Orestes, Oliveira, Karin Carneiro, Ávila, Victor Ferreira, Arias, Simone Costa Alarcon, Seguro, Antonio Carlos, Malheiros, Denise Maria Avancini Costa, Camara, Niels Olsen Saraiva, Fujihara, Clarice Kazue, Zatz, Roberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293269/ https://www.ncbi.nlm.nih.gov/pubmed/34305624 http://dx.doi.org/10.3389/fphys.2021.606392

Ejemplares similares

Simultaneous activation of innate and adaptive immunity participates in the development of renal injury in a model of heavy proteinuria
por: Faustino, Viviane Dias, et al.
Publicado: (2018)

NF-κB System Is Chronically Activated and Promotes Glomerular Injury in Experimental Type 1 Diabetic Kidney Disease
por: Foresto-Neto, Orestes, et al.
Publicado: (2020)

Regression of Albuminuria and Hypertension and Arrest of Severe Renal Injury by a Losartan-Hydrochlorothiazide Association in a Model of Very Advanced Nephropathy
por: Arias, Simone Costa Alarcon, et al.
Publicado: (2013)

Inflammation in Renal Diseases: New and Old Players
por: Andrade-Oliveira, Vinicius, et al.
Publicado: (2019)

Innate And Adaptive Immunity are Progressively Activated in Parallel with Renal Injury in the 5/6 Renal Ablation Model
por: Fanelli, Camilla, et al.
Publicado: (2017)

Gut Microbiota and Intestinal Epithelial Myd88 Signaling Are Crucial for Renal Injury in UUO Mice
por: Watanabe, Ingrid Kazue Mizuno, et al.
Publicado: (2020)

A Novel Aldosterone Antagonist Limits Renal Injury in 5/6 Nephrectomy
por: Fujihara, Clarice K., et al.
Publicado: (2017)

Effect of Renal Embolization with Trisacryl and PAVc
por: de Assis Barbosa, Leandro, et al.
Publicado: (2009)

Chronic VEGF Blockade Worsens Glomerular Injury in the Remnant Kidney Model
por: Machado, Flavia G., et al.
Publicado: (2012)

Protection of renal tubules against gentamicin induced nephrotoxicity
por: Tavafi, Majid
Publicado: (2013)

Oxymatrine Alleviates Gentamicin-Induced Renal Injury in Rats
por: Kang, Songyao, et al.
Publicado: (2022)

Effect of endogenous hydrogen sulfide inhibition on structural and functional renal disturbances induced by gentamicin
por: Francescato, H.D.C., et al.
Publicado: (2012)

Protective response in renal transplantation: no clinical or molecular differences between open and laparoscopic donor nephrectomy
por: Machado, Christiano, et al.
Publicado: (2013)

Cardiac and renal effects of liver cirrhosis in a growing animal model
por: Tannuri, Ana Cristina Aoun, et al.
Publicado: (2021)

Ameliorative effects of metformin on renal histologic and biochemical alterations of gentamicin-induced renal toxicity in Wistar rats
por: Nasri, Hamid
Publicado: (2013)

Ameliorative effects of metformin on renal histologic and biochemical alterations of gentamicin-induced renal toxicity in Wistar rats
por: Amini, Fatemeh Ghaed, et al.
Publicado: (2012)

Nephroprotective potential of Graptophyllum pictum against renal injury induced by gentamicin
por: Srinivasan, Keloth Kaitheri, et al.
Publicado: (2015)

The impact of hypoxia-inducible factors in the pathogenesis of kidney diseases: a link through cell metabolism
por: Foresto-Neto, Orestes, et al.
Publicado: (2023)

Gentamicin Induced Apoptosis of Renal Tubular Epithelial (LLC-PK(1)) Cells
por: Choi, Kyu Hun, et al.
Publicado: (2000)

A Uremic Goat Model Created by Subtotal Renal Artery Embolization and Gentamicin
por: van Gelder, Maaike K., et al.
Publicado: (2021)

Nephroprotective Effect of Ursolic Acid in a Murine Model of Gentamicin-Induced Renal Damage
por: Pai, Preethi G., et al.
Publicado: (2012)

Histopathological study of the combination of metformin and garlic juice for the attenuation of gentamicin renal toxicity in rats
por: Baradaran, Azar, et al.
Publicado: (2013)

Thymoquinone and curcumin attenuate gentamicin-induced renal oxidative stress, inflammation and apoptosis in rats
por: Mahmoud, Ayman M, et al.
Publicado: (2014)

Chemopreventive role of Coriandrum sativum against gentamicin-induced renal histopathological damage in rats
por: Lakhera, Abhijeet, et al.
Publicado: (2015)

Mentha piperita in nephrotoxicity – a possible intervention to ameliorate renal derangements associated with gentamicin
por: Ullah, Naveed, et al.
Publicado: (2014)

Gentamicin induced acute renal damage and its evaluation using urinary biomarkers in rats
por: Udupa, Venkatesha, et al.
Publicado: (2018)

Protective effect of pomegranate flower extract against gentamicin-induced renal toxicity in male rats
por: Sadeghi, Ferdos, et al.
Publicado: (2015)

Lack of Nephroprotective Efficacy of Althaea Officinalis Flower Extract Against Gentamicin Renal Toxicity in Male Rats
por: Talebi, Ardeshir, et al.
Publicado: (2014)

Dose recommendations for gentamicin in the real-world obese population with varying body weight and renal (dys)function
por: Smit, Cornelis, et al.
Publicado: (2020)

Renal proximal tubulopathy in an HIV-infected patient treated with tenofovir alafenamide and gentamicin: a case report
por: Heron, Jack E., et al.
Publicado: (2020)

Punica granatum improves renal function in gentamicin-induced nephropathy in rats via attenuation of oxidative stress
por: Mestry, Snehal N., et al.
Publicado: (2020)

Impact of Human Umbilical Cord Blood Mononuclear Cells on Gentamicin-Induced Renal Injury and Genotoxicity in Rats
por: Abu Almaaty, Ali H., et al.
Publicado: (2021)

Population Pharmacokinetics and Dosing Optimization of Gentamicin in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy
por: He, Sha, et al.
Publicado: (2022)

Tigecycline and Gentamicin-Combined Treatment Enhances Renal Damage: Oxidative Stress, Inflammatory Reaction, and Apoptosis Interplay
por: Elgazzar, Dina, et al.
Publicado: (2022)

Role of cineole in alleviation of acute kidney injury and renal function recovery following gentamicin administration in rats
por: Rahimi Monfared, Sobhan, et al.
Publicado: (2023)

Efficacy of hemodiafiltration on the outcome of renal and respiratory failure of leptospirosis
por: Andrade, LC, et al.
Publicado: (2001)

N-Acetylcysteine Protects Rats with Chronic Renal Failure from Gadolinium-Chelate Nephrotoxicity
por: Pereira, Leonardo Victor Barbosa, et al.
Publicado: (2012)

Editorial: The role of micronutrients in renal physiology and pathophysiology
por: Hryciw, Deanne H., et al.
Publicado: (2023)

HPLC Analysis and In Vivo Renoprotective Evaluation of Hydroalcoholic Extract of Cucumis melo Seeds in Gentamicin-Induced Renal Damage
por: Saleem, Mohammad, et al.
Publicado: (2019)

Increased Expression of Heat Shock Protein 72 Protects Renal Proximal Tubular Cells from Gentamicin-induced Injury
por: Wang, Zhipeng, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_i5gu2pf4ndmk39u1s46j8gos1b