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Comparison of Lethal and Nonlethal Mouse Models of Orientia tsutsugamushi Infection Reveals T-Cell Population-Associated Cytokine Signatures Correlated with Lethality and Protection

The antigenic diversity of Orientia tsutsugamushi as well as the interstrain difference(s) associated with virulence in mice impose the necessity to dissect the host immune response. In this study we compared the host response in lethal and non-lethal murine models of O. tsutsugamushi infection usin...

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Detalles Bibliográficos
Autores principales: Luce-Fedrow, Alison, Chattopadhyay, Suchismita, Chan, Teik-Chye, Pearson, Gregory, Patton, John B., Richards, Allen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293330/
https://www.ncbi.nlm.nih.gov/pubmed/34287349
http://dx.doi.org/10.3390/tropicalmed6030121