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In Vitro Reconstitution of Yeast Translation System Capable of Synthesizing Long Polypeptide and Recapitulating Programmed Ribosome Stalling

The rates of translation elongation or termination in eukaryotes are modulated through cooperative molecular interactions involving mRNA, the ribosome, aminoacyl- and nascent polypeptidyl-tRNAs, and translation factors. To investigate the molecular mechanisms underlying these processes, we developed...

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Detalles Bibliográficos
Autores principales: Nagai, Riku, Xu, Yichen, Liu, Chang, Shimabukuro, Ayaka, Takeuchi-Tomita, Nono
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293373/
https://www.ncbi.nlm.nih.gov/pubmed/34287320
http://dx.doi.org/10.3390/mps4030045