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H2B Type 1-K Accumulates in Senescent Fibroblasts with Persistent DNA Damage along with Methylated and Phosphorylated Forms of HMGA1

Cellular senescence is a state of terminal proliferative arrest that plays key roles in aging by preventing stem cell renewal and by inducing the expression of a series of inflammatory factors including many secreted proteins with paracrine effects. The in vivo identification of senescent cells is d...

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Detalles Bibliográficos
Autores principales: Contrepois, Kévin, Mann, Carl, Fenaille, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293446/
https://www.ncbi.nlm.nih.gov/pubmed/34205514
http://dx.doi.org/10.3390/proteomes9020030