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NLRP3 inhibition attenuates early brain injury and delayed cerebral vasospasm after subarachnoid hemorrhage
BACKGROUND: The NLRP3 inflammasome is a critical mediator of several vascular diseases through positive regulation of proinflammatory pathways. In this study, we defined the role of NLRP3 in both the acute and delayed phases following subarachnoid hemorrhage (SAH). SAH is associated with devastating...
Autores principales: | Dodd, William S., Noda, Imaray, Martinez, Melanie, Hosaka, Koji, Hoh, Brian L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293512/ https://www.ncbi.nlm.nih.gov/pubmed/34284798 http://dx.doi.org/10.1186/s12974-021-02207-x |
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