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BHLHE40 Regulates IL-10 and IFN-γ Production in T Cells but Does Not Interfere With Human Type 1 Regulatory T Cell Differentiation

Type 1 regulatory T (Tr1) cells are subset of peripherally induced antigen-specific regulatory T cells. IL-10 signaling has been shown to be indispensable for polarization and function of Tr1 cells. However, the transcriptional machinery underlying human Tr1 cell differentiation and function is not...

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Detalles Bibliográficos
Autores principales: Uyeda, Molly Javier, Freeborn, Robert A., Cieniewicz, Brandon, Romano, Rosa, Chen, Ping (Pauline), Liu, Jeffrey Mao-Hwa, Thomas, Benjamin, Lee, Esmond, Cepika, Alma-Martina, Bacchetta, Rosa, Roncarolo, Maria Grazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293608/
https://www.ncbi.nlm.nih.gov/pubmed/34305917
http://dx.doi.org/10.3389/fimmu.2021.683680