Brief Guide: Experimental Strategies for High-Quality Hit Selection from Small-Molecule Screening Campaigns

Small-molecule screening is a powerful approach to identify modulators of either specific biological targets or cellular pathways with phenotypic endpoints. A myriad of assay technologies are available to assess the activity of enzymes, monitor protein–protein interactions, measure transcription fac...

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Detalles Bibliográficos
Autores principales: Rothenaigner, Ina, Hadian, Kamyar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293735/
https://www.ncbi.nlm.nih.gov/pubmed/33882754
http://dx.doi.org/10.1177/24725552211008862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293735/
https://www.ncbi.nlm.nih.gov/pubmed/33882754
http://dx.doi.org/10.1177/24725552211008862

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