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Brief Guide: Experimental Strategies for High-Quality Hit Selection from Small-Molecule Screening Campaigns
Small-molecule screening is a powerful approach to identify modulators of either specific biological targets or cellular pathways with phenotypic endpoints. A myriad of assay technologies are available to assess the activity of enzymes, monitor protein–protein interactions, measure transcription fac...
Autores principales: | Rothenaigner, Ina, Hadian, Kamyar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293735/ https://www.ncbi.nlm.nih.gov/pubmed/33882754 http://dx.doi.org/10.1177/24725552211008862 |
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