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TRPV1 Antagonist Prevents Neonatal Sevoflurane-Induced Synaptic Abnormality and Cognitive Impairment in Mice Through Regulating the Src/Cofilin Signaling Pathway

Long-term neurodevelopmental disorders following neonatal anesthesia have been reported both in young animals and in children. The activation of transient receptor potential vanilloid 1 (TRPV1) channels in hippocampus adversely affects neurodevelopment. The current study explored the underlying mech...

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Detalles Bibliográficos
Autores principales: Liu, Yuqiang, Yang, Han, Fu, Yifei, Pan, Zhenglong, Qiu, Fang, Xu, Yanwen, Yang, Xinping, Chen, Qian, Ma, Daqing, Liu, Zhiheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293754/
https://www.ncbi.nlm.nih.gov/pubmed/34307363
http://dx.doi.org/10.3389/fcell.2021.684516