GuidingNet: revealing transcriptional cofactor and predicting binding for DNA methyltransferase by network regularization

The DNA methyltransferases (DNMTs) (DNMT3A, DNMT3B and DNMT3L) are primarily responsible for the establishment of genomic locus-specific DNA methylation patterns, which play an important role in gene regulation and animal development. However, this important protein family’s binding mechanism, i.e....

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Detalles Bibliográficos
Autores principales: Ren, Lixin, Gao, Caixia, Duren, Zhana, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Problem Solving Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293812/
https://www.ncbi.nlm.nih.gov/pubmed/33048117
http://dx.doi.org/10.1093/bib/bbaa245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293812/
https://www.ncbi.nlm.nih.gov/pubmed/33048117
http://dx.doi.org/10.1093/bib/bbaa245

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