Cargando…
GuidingNet: revealing transcriptional cofactor and predicting binding for DNA methyltransferase by network regularization
The DNA methyltransferases (DNMTs) (DNMT3A, DNMT3B and DNMT3L) are primarily responsible for the establishment of genomic locus-specific DNA methylation patterns, which play an important role in gene regulation and animal development. However, this important protein family’s binding mechanism, i.e....
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293812/ https://www.ncbi.nlm.nih.gov/pubmed/33048117 http://dx.doi.org/10.1093/bib/bbaa245 |