Enhanced Production of (S)-2-arylpropionic Acids by Protein Engineering and Whole-Cell Catalysis

Esterases are important biocatalysts for chemical synthesis. Several bHSL family esterases have been used to prepare (S)-2-arylpropionic acids with stronger anti-inflammatory effects via kinetic resolution. Here, we presented the discovery of key residues that controlled the enantioselectivity of bH...

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Detalles Bibliográficos
Autores principales: Liu, Xiaolong, Zhao, Meng, Fan, Xinjiong, Fu, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293918/
https://www.ncbi.nlm.nih.gov/pubmed/34307324
http://dx.doi.org/10.3389/fbioe.2021.697677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293918/
https://www.ncbi.nlm.nih.gov/pubmed/34307324
http://dx.doi.org/10.3389/fbioe.2021.697677

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