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Inflammasome-Induced Osmotic Pressure and the Mechanical Mechanisms Underlying Astrocytic Swelling and Membrane Blebbing in Pyroptosis

Cell swelling and membrane blebbing are characteristic of pyroptosis. In the present study, we explored the role of intracellular tension activity in the deformation of pyroptotic astrocytes. Protein nanoparticle-induced osmotic pressure (PN-OP) was found to be involved in cell swelling and membrane...

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Detalles Bibliográficos
Autores principales: Zheng, Zihui, Wang, Tingting, Chen, Jiahui, Qiu, Huimin, Zhang, Chencheng, Liu, Weizhen, Qin, Simiao, Tian, Jilai, Guo, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293990/
https://www.ncbi.nlm.nih.gov/pubmed/34305921
http://dx.doi.org/10.3389/fimmu.2021.688674