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Identification and Immune Assessment of T Cell Epitopes in Five Plasmodium falciparum Blood Stage Antigens to Facilitate Vaccine Candidate Selection and Optimization

The hurdles to effective blood stage malaria vaccine design include immune evasion tactics used by the parasite such as redundant invasion pathways and antigen variation among circulating parasite strains. While blood stage malaria vaccine development primarily focuses on eliciting optimal humoral r...

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Detalles Bibliográficos
Autores principales: Kotraiah, Vinayaka, Phares, Timothy W., Terry, Frances E., Hindocha, Pooja, Silk, Sarah E., Nielsen, Carolyn M., Moise, Leonard, Tucker, Kenneth D., Ashfield, Rebecca, Martin, William D., De Groot, Anne S., Draper, Simon J., Gutierrez, Gabriel M., Noe, Amy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294059/
https://www.ncbi.nlm.nih.gov/pubmed/34305923
http://dx.doi.org/10.3389/fimmu.2021.690348