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KiRNet: Kinase-centered network propagation of pharmacological screen results

The ever-increasing size and scale of biological information have popularized network-based approaches as a means to interpret these data. We develop a network propagation method that integrates kinase-inhibitor-focused functional screens with known protein-protein interactions (PPIs). This method,...

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Detalles Bibliográficos
Autores principales: Bello, Thomas, Chan, Marina, Golkowski, Martin, Xue, Andrew G., Khasnavis, Nithisha, Ceribelli, Michele, Ong, Shao-En, Thomas, Craig J., Gujral, Taranjit S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294099/
https://www.ncbi.nlm.nih.gov/pubmed/34296206
http://dx.doi.org/10.1016/j.crmeth.2021.100007