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KiRNet: Kinase-centered network propagation of pharmacological screen results
The ever-increasing size and scale of biological information have popularized network-based approaches as a means to interpret these data. We develop a network propagation method that integrates kinase-inhibitor-focused functional screens with known protein-protein interactions (PPIs). This method,...
Autores principales: | Bello, Thomas, Chan, Marina, Golkowski, Martin, Xue, Andrew G., Khasnavis, Nithisha, Ceribelli, Michele, Ong, Shao-En, Thomas, Craig J., Gujral, Taranjit S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294099/ https://www.ncbi.nlm.nih.gov/pubmed/34296206 http://dx.doi.org/10.1016/j.crmeth.2021.100007 |
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