Cargando…

Tripchlorolide attenuates β-amyloid generation by inducing NEP activity in N2a/APP695 cells

BACKGROUND AND PURPOSE: Alzheimer’s disease (AD) is a neurodegeneration disease. The previous work from our research group demonstrated the neuroprotective effects of tripchlorolide (T4) in AD animal models. MATERIALS AND METHODS: Neprilysin (NEP) is known as an important physiological amyloid-β pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Zeng, Yuqi, Li, Yongkun, Shen, Hui, Lin, Nan, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294110/
https://www.ncbi.nlm.nih.gov/pubmed/34316383
http://dx.doi.org/10.1515/tnsci-2020-0178