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Pathogenic Role of Circulating Citrullinated Antigens and Anti-Cyclic Monoclonal Citrullinated Peptide Antibodies in Rheumatoid Arthritis

We examined whether it is possible to directly detect citrullinated antigens in the serum of rheumatoid arthritis (RA) patients using a monoclonal antibody (mAb) designed to be specific for citrullinated peptides. In order to confirm the potential of the mAb as a direct arthritis-inducing substance...

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Detalles Bibliográficos
Autores principales: Won, Pureun, Kim, Youngkyun, Jung, Hyerin, Rim, Yeri Alice, Sohn, Dong Hyun, Robinson, William H., Moon, Su-Jin, Ju, Ji Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294326/
https://www.ncbi.nlm.nih.gov/pubmed/34305925
http://dx.doi.org/10.3389/fimmu.2021.692242