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DAF-18/PTEN inhibits germline zygotic gene activation during primordial germ cell quiescence
Quiescence, an actively-maintained reversible state of cell cycle arrest, is not well understood. PTEN is one of the most frequently lost tumor suppressors in human cancers and regulates quiescence of stem cells and cancer cells. The sole PTEN ortholog in Caenorhabditis elegans is daf-18. In a C. el...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294487/ https://www.ncbi.nlm.nih.gov/pubmed/34288923 http://dx.doi.org/10.1371/journal.pgen.1009650 |