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DAF-18/PTEN inhibits germline zygotic gene activation during primordial germ cell quiescence

Quiescence, an actively-maintained reversible state of cell cycle arrest, is not well understood. PTEN is one of the most frequently lost tumor suppressors in human cancers and regulates quiescence of stem cells and cancer cells. The sole PTEN ortholog in Caenorhabditis elegans is daf-18. In a C. el...

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Detalles Bibliográficos
Autores principales:	Fry, Amanda L., Webster, Amy K., Burnett, Julia, Chitrakar, Rojin, Baugh, L. Ryan, Hubbard, E. Jane Albert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294487/ https://www.ncbi.nlm.nih.gov/pubmed/34288923 http://dx.doi.org/10.1371/journal.pgen.1009650

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