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Pore-forming alpha-hemolysin efficiently improves the immunogenicity and protective efficacy of protein antigens

Highly immunogenic exotoxins are used as carrier proteins because they efficiently improve the immunogenicity of polysaccharides. However, their efficiency with protein antigens remains unclear. In the current study, the candidate antigen PA0833 from Pseudomonas aeruginosa was fused to the α-hemolys...

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Detalles Bibliográficos
Autores principales: Zou, Jin-Tao, Jing, Hai-Ming, Yuan, Yue, Lei, Lang-Huan, Chen, Zhi-Fu, Gou, Qiang, Xiong, Qing-Shan, Zhang, Xiao-Li, Zhao, Zhuo, Zhang, Xiao-Kai, Zeng, Hao, Zou, Quan-Ming, Zhang, Jin-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294524/
https://www.ncbi.nlm.nih.gov/pubmed/34288976
http://dx.doi.org/10.1371/journal.ppat.1009752