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Pore-forming alpha-hemolysin efficiently improves the immunogenicity and protective efficacy of protein antigens
Highly immunogenic exotoxins are used as carrier proteins because they efficiently improve the immunogenicity of polysaccharides. However, their efficiency with protein antigens remains unclear. In the current study, the candidate antigen PA0833 from Pseudomonas aeruginosa was fused to the α-hemolys...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294524/ https://www.ncbi.nlm.nih.gov/pubmed/34288976 http://dx.doi.org/10.1371/journal.ppat.1009752 |