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Current challenges for unseen-epitope TCR interaction prediction and a new perspective derived from image classification

The prediction of epitope recognition by T-cell receptors (TCRs) has seen many advancements in recent years, with several methods now available that can predict recognition for a specific set of epitopes. However, the generic case of evaluating all possible TCR-epitope pairs remains challenging, mai...

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Detalles Bibliográficos
Autores principales: Moris, Pieter, De Pauw, Joey, Postovskaya, Anna, Gielis, Sofie, De Neuter, Nicolas, Bittremieux, Wout, Ogunjimi, Benson, Laukens, Kris, Meysman, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294552/
https://www.ncbi.nlm.nih.gov/pubmed/33346826
http://dx.doi.org/10.1093/bib/bbaa318