Anti–platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein

Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a severe adverse effect of ChAdOx1 nCoV-19 COVID-19 vaccine (Vaxzevria) and Janssen Ad26.COV2.S COVID-19 vaccine, and it is associated with unusual thrombosis. VITT is caused by anti-platelet factor 4 (PF4) antibodies activating platelets...

Descripción completa

Detalles Bibliográficos
Autores principales: Greinacher, Andreas, Selleng, Kathleen, Mayerle, Julia, Palankar, Raghavendra, Wesche, Jan, Reiche, Sven, Aebischer, Andrea, Warkentin, Theodore E., Muenchhoff, Maximilian, Hellmuth, Johannes C., Keppler, Oliver T., Duerschmied, Daniel, Lother, Achim, Rieg, Siegbert, Gawaz, Meinrad Paul, Mueller, Karin Anne Lydia, Scheer, Christian S., Napp, Matthias, Hahnenkamp, Klaus, Lucchese, Guglielmo, Vogelgesang, Antje, Flöel, Agnes, Lovreglio, Piero, Stufano, Angela, Marschalek, Rolf, Thiele, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Thrombosis and Hemostasis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294553/
https://www.ncbi.nlm.nih.gov/pubmed/34280256
http://dx.doi.org/10.1182/blood.2021012938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294553/
https://www.ncbi.nlm.nih.gov/pubmed/34280256
http://dx.doi.org/10.1182/blood.2021012938

Ejemplares similares