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Recessive/dominant model: Alternative choice in case-control-based genome-wide association studies

An additive genetic model is usually employed in case-control-based genome-wide association studies. The model usually encodes "AA", "Aa" and "aa" ("a" represents the minor allele) as three different numbers, implying the contribution of genotype "Aa"...

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Detalles Bibliográficos
Autores principales: Liu, Han-Ming, Zheng, Jin-Ping, Yang, Dan, Liu, Zhao-Fa, Li, Zi, Hu, Zhen-Zhen, Li, Ze-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294554/
https://www.ncbi.nlm.nih.gov/pubmed/34288964
http://dx.doi.org/10.1371/journal.pone.0254947