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Associations between plasma nucleoside reverse transcriptase inhibitors concentrations and cognitive function in people with HIV

OBJECTIVES: To investigate the associations of plasma lamivudine (3TC), abacavir (ABC), emtricitabine (FTC) and tenofovir (TFV) concentrations with cognitive function in a cohort of treated people with HIV (PWH). METHODS: Pharmacokinetics (PK) and cognitive function (Cogstate, six domains) data were...

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Detalles Bibliográficos
Autores principales: De Francesco, Davide, Wang, Xinzhu, Dickinson, Laura, Underwood, Jonathan, Bagkeris, Emmanouil, Babalis, Daphne S., Mallon, Patrick W. G., Post, Frank A., Vera, Jaime H., Sachikonye, Memory, Williams, Ian, Khoo, Saye, Sabin, Caroline A., Winston, Alan, Boffito, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294567/
https://www.ncbi.nlm.nih.gov/pubmed/34288920
http://dx.doi.org/10.1371/journal.pone.0253861