Molecular basis of anticoagulant and anticomplement activity of the tick salivary protein Salp14 and its homologs

During feeding, a tick's mouthpart penetrates the host's skin and damages tissues and small blood vessels, triggering the extrinsic coagulation and lectin complement pathways. To elude these defense mechanisms, ticks secrete multiple anticoagulant proteins and complement system inhibitors...

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Detalles Bibliográficos
Autores principales: Denisov, Stepan S., Ippel, Johannes H., Castoldi, Elisabetta, Mans, Ben J., Hackeng, Tilman M., Dijkgraaf, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294578/
https://www.ncbi.nlm.nih.gov/pubmed/34118237
http://dx.doi.org/10.1016/j.jbc.2021.100865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294578/
https://www.ncbi.nlm.nih.gov/pubmed/34118237
http://dx.doi.org/10.1016/j.jbc.2021.100865

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