Cargando…

Molecular determinants for α-tubulin methylation by SETD2

Post-translational modifications to tubulin are important for many microtubule-based functions inside cells. It was recently shown that methylation of tubulin by the histone methyltransferase SETD2 occurs on mitotic spindle microtubules during cell division, with its absence resulting in mitotic def...

Descripción completa

Detalles Bibliográficos
Autores principales: Kearns, Sarah, Mason, Frank M., Rathmell, W. Kimryn, Park, In Young, Walker, Cheryl, Verhey, Kristen J., Cianfrocco, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294582/
https://www.ncbi.nlm.nih.gov/pubmed/34157286
http://dx.doi.org/10.1016/j.jbc.2021.100898