Ca(2+)/calmodulin kinase II–dependent regulation of β(IV)-spectrin modulates cardiac fibroblast gene expression, proliferation, and contractility

Fibrosis is a pronounced feature of heart disease and the result of dysregulated activation of resident cardiac fibroblasts (CFs). Recent work identified stress-induced degradation of the cytoskeletal protein β(IV)-spectrin as an important step in CF activation and cardiac fibrosis. Furthermore, los...

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Detalles Bibliográficos
Autores principales: Nassal, Drew M., Patel, Nehal J., Unudurthi, Sathya D., Shaheen, Rebecca, Yu, Jane, Mohler, Peter J., Hund, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294584/
https://www.ncbi.nlm.nih.gov/pubmed/34153319
http://dx.doi.org/10.1016/j.jbc.2021.100893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294584/
https://www.ncbi.nlm.nih.gov/pubmed/34153319
http://dx.doi.org/10.1016/j.jbc.2021.100893

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