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Roles of constitutive and signal-dependent protein phosphatase 2A docking motifs in burst attenuation of the cyclic AMP response element-binding protein
The cAMP response element-binding protein (CREB) is an important regulator of cell growth, metabolism, and synaptic plasticity. CREB is activated through phosphorylation of an evolutionarily conserved Ser residue (S133) within its intrinsically disordered kinase-inducible domain (KID). Phosphorylati...
Autores principales: | Kim, Sang Hwa, Wu, Cheng-Guo, Jia, Weiyan, Xing, Yongna, Tibbetts, Randal S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294589/ https://www.ncbi.nlm.nih.gov/pubmed/34171357 http://dx.doi.org/10.1016/j.jbc.2021.100908 |
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