A Novel Liver-targeted Testosterone Therapy for Sarcopenia in Androgen Deprived Men With Prostate Cancer

OBJECTIVE: Androgen deprivation therapy (ADT) reduces muscle and bone mass, increasing frailty in men with prostate cancer. The liver mediates the whole body anabolic effects of testosterone. Based on first-pass metabolism, liver-targeted testosterone treatment (LTTT) entails oral delivery of a smal...

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Detalles Bibliográficos
Autores principales: Rhee, Handoo, Navaratnam, Anojan, Oleinikova, Irina, Gilroy, Deborah, Scuderi, Yolanda, Heathcote, Peter, Nguyen, Tuan, Wood, Simon, Ho, Ken K Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294688/
https://www.ncbi.nlm.nih.gov/pubmed/34308090
http://dx.doi.org/10.1210/jendso/bvab116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294688/
https://www.ncbi.nlm.nih.gov/pubmed/34308090
http://dx.doi.org/10.1210/jendso/bvab116

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