PGD(2) and CRTH2 counteract Type 2 cytokine–elicited intestinal epithelial responses during helminth infection

Type 2 inflammation is associated with epithelial cell responses, including goblet cell hyperplasia, that promote worm expulsion during intestinal helminth infection. How these epithelial responses are regulated remains incompletely understood. Here, we show that mice deficient in the prostaglandin...

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Detalles Bibliográficos
Autores principales: Oyesola, Oyebola O., Shanahan, Michael T., Kanke, Matt, Mooney, Bridget M., Webb, Lauren M., Smita, Shuchi, Matheson, Macy K., Campioli, Pamela, Pham, Duc, Früh, Simon P., McGinty, John W., Churchill, Madeline J., Cahoon, Jordan L., Sundaravaradan, Pavithra, Flitter, Becca A., Mouli, Karthik, Nadjsombati, Marija S., Kamynina, Elena, Peng, Seth A., Cubitt, Rebecca L., Gronert, Karsten, Lord, James D., Rauch, Isabella, von Moltke, Jakob, Sethupathy, Praveen, Tait Wojno, Elia D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294949/
https://www.ncbi.nlm.nih.gov/pubmed/34283207
http://dx.doi.org/10.1084/jem.20202178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294949/
https://www.ncbi.nlm.nih.gov/pubmed/34283207
http://dx.doi.org/10.1084/jem.20202178

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