Histone Methyltransferase G9a Promotes the Development of Renal Cancer through Epigenetic Silencing of Tumor Suppressor Gene SPINK5

BACKGROUND: Renal cell carcinoma (RCC) accounts for approximately 2–3% of malignant tumors in adults, while clear cell renal cell carcinoma accounts for 70–85% of kidney cancer cases, with an increasing incidence worldwide. G9a is the second histone methyltransferase found in mammals, catalyzing lys...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Ren-Gui, Deng, Huan, Liu, Xiu-Heng, Chen, Zhi-yuan, Wan, Shan-shan, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294961/
https://www.ncbi.nlm.nih.gov/pubmed/34336110
http://dx.doi.org/10.1155/2021/6650781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294961/
https://www.ncbi.nlm.nih.gov/pubmed/34336110
http://dx.doi.org/10.1155/2021/6650781

Ejemplares similares