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Histone Methyltransferase G9a Promotes the Development of Renal Cancer through Epigenetic Silencing of Tumor Suppressor Gene SPINK5

BACKGROUND: Renal cell carcinoma (RCC) accounts for approximately 2–3% of malignant tumors in adults, while clear cell renal cell carcinoma accounts for 70–85% of kidney cancer cases, with an increasing incidence worldwide. G9a is the second histone methyltransferase found in mammals, catalyzing lys...

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Detalles Bibliográficos
Autores principales:	Li, Ren-Gui, Deng, Huan, Liu, Xiu-Heng, Chen, Zhi-yuan, Wan, Shan-shan, Wang, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294961/ https://www.ncbi.nlm.nih.gov/pubmed/34336110 http://dx.doi.org/10.1155/2021/6650781

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