1-Nitropyrene Induced Reactive Oxygen Species–Mediated Apoptosis in Macrophages through AIF Nuclear Translocation and AMPK/Nrf-2/HO-1 Pathway Activation

1-Nitropyrene (1-NP), one of the most abundant nitropolycyclic aromatic hydrocarbons (nitro-PAHs), is generated from the incomplete combustion of carbonaceous organic compounds. 1-NP is a specific marker of diesel exhaust and is an environmental pollutant and a probable carcinogen. Macrophages parti...

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Detalles Bibliográficos
Autores principales: Su, Chun-Hung, Ho, Yung-Chuan, Lee, Min-Wei, Tseng, Ching-Chi, Lee, Shiuan-Shinn, Hsieh, Ming Kun, Chen, Hsin-Hung, Lee, Chien-Ying, Wu, Sheng-Wen, Kuan, Yu-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294986/
https://www.ncbi.nlm.nih.gov/pubmed/34336119
http://dx.doi.org/10.1155/2021/9314342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294986/
https://www.ncbi.nlm.nih.gov/pubmed/34336119
http://dx.doi.org/10.1155/2021/9314342

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