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1-Nitropyrene Induced Reactive Oxygen Species–Mediated Apoptosis in Macrophages through AIF Nuclear Translocation and AMPK/Nrf-2/HO-1 Pathway Activation
1-Nitropyrene (1-NP), one of the most abundant nitropolycyclic aromatic hydrocarbons (nitro-PAHs), is generated from the incomplete combustion of carbonaceous organic compounds. 1-NP is a specific marker of diesel exhaust and is an environmental pollutant and a probable carcinogen. Macrophages parti...
Autores principales: | Su, Chun-Hung, Ho, Yung-Chuan, Lee, Min-Wei, Tseng, Ching-Chi, Lee, Shiuan-Shinn, Hsieh, Ming Kun, Chen, Hsin-Hung, Lee, Chien-Ying, Wu, Sheng-Wen, Kuan, Yu-Hsiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294986/ https://www.ncbi.nlm.nih.gov/pubmed/34336119 http://dx.doi.org/10.1155/2021/9314342 |
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