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Metformin Inhibits the Development of Hypopharyngeal Squamous Cell Carcinoma through Circ_0003214-Mediated MiR-489-3p-ADAM10 Pathway

PURPOSE: This study aims to explore the function of metformin in hypopharyngeal squamous cell carcinoma (HSCC) and the underlying mechanism. METHODS: Cell viability, colony formation, cell apoptosis, and cell cycle were investigated using cell counting kit-8 assay, colony formation, and flow cytomet...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoqiang, Li, Chen, Chen, Wei, Lin, Shuchun, Yi, Xuehan, Lin, Qin, Xu, Hao, Wang, Desheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295003/
https://www.ncbi.nlm.nih.gov/pubmed/34335751
http://dx.doi.org/10.1155/2021/2265475