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Cytoplasmic ADP-ribosylation levels correlate with markers of patient outcome in distinct human cancers

ADP-ribosylation (ADPR) is a posttranslational modification whose importance in oncology keeps increasing due to frequent use of PARP inhibitors (PARPi) to treat different tumor types. Due to the lack of suitable tools to analyze cellular ADPR levels, ADPR’s significance for cancer progression and p...

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Detalles Bibliográficos
Autores principales: Aimi, Fabio, Moch, Holger, Schraml, Peter, Hottiger, Michael O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295037/
https://www.ncbi.nlm.nih.gov/pubmed/33742140
http://dx.doi.org/10.1038/s41379-021-00788-9