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Cytoplasmic ADP-ribosylation levels correlate with markers of patient outcome in distinct human cancers
ADP-ribosylation (ADPR) is a posttranslational modification whose importance in oncology keeps increasing due to frequent use of PARP inhibitors (PARPi) to treat different tumor types. Due to the lack of suitable tools to analyze cellular ADPR levels, ADPR’s significance for cancer progression and p...
Autores principales: | Aimi, Fabio, Moch, Holger, Schraml, Peter, Hottiger, Michael O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295037/ https://www.ncbi.nlm.nih.gov/pubmed/33742140 http://dx.doi.org/10.1038/s41379-021-00788-9 |
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