CYP2D6 GENOTYPE AND REDUCED CODEINE ANALGESIC EFFECT IN REAL-WORLD CLINICAL PRACTICE

Cytochrome P450 2D6 (CYP2D6) O-demethylates codeine to the active drug, morphine. However, the utility of testing for CYP2D6 metabolizer status in patients receiving codeine in real-world clinical practice is poorly defined. Using data from a DNA bank linked to de-identified electronic health record...

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Detalles Bibliográficos
Autores principales: Carranza-Leon, Daniel, Dickson, Alyson L., Gaedigk, Andrea, Stein, C. Michael, Chung, Cecilia P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295171/
https://www.ncbi.nlm.nih.gov/pubmed/33750887
http://dx.doi.org/10.1038/s41397-021-00226-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295171/
https://www.ncbi.nlm.nih.gov/pubmed/33750887
http://dx.doi.org/10.1038/s41397-021-00226-8

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