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A hypothesis for the pathogenesis of radiation-induced oral mucositis: when biological challenges exceed physiologic protective mechanisms. Implications for pharmacological prevention and treatment
Oral mucositis (OM) remains a significant unmet need for patients being treated with standard concomitant chemoradiation (CRT) regimens for head and neck cancers (HNC). OM’s pathogenesis is complex and includes both direct and indirect damage pathways. In this paper, the field is reviewed with empha...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295245/ https://www.ncbi.nlm.nih.gov/pubmed/33712912 http://dx.doi.org/10.1007/s00520-021-06108-w |