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CD276 is an important player in macrophage recruitment into the tumor and an upstream regulator for PAI-1

More than 70% of colorectal, prostate, ovarian, pancreatic and breast cancer specimens show expression of CD276 (B7–H3), a potential immune checkpoint family member. Several studies have shown that high CD276 expression in cancer cells correlates with a poor clinical prognosis. This has been associa...

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Detalles Bibliográficos
Autores principales: Durlanik, Sibel, Fundel-Clemens, Katrin, Viollet, Coralie, Huber, Heinrich J., Lenter, Martin, Kitt, Kerstin, Pflanz, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295264/
https://www.ncbi.nlm.nih.gov/pubmed/34290311
http://dx.doi.org/10.1038/s41598-021-94360-9