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Genome-wide CRISPR/Cas9 screening identifies CARHSP1 responsible for radiation resistance in glioblastoma

Glioblastomas (GBM) is the most common primary malignant brain tumor, and radiotherapy plays a critical role in its therapeutic management. Unfortunately, the development of radioresistance is universal. Here, we identified calcium-regulated heat-stable protein 1 (CARHSP1) as a critical driver for r...

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Detalles Bibliográficos
Autores principales: Zhu, Guo-dong, Yu, Jing, Sun, Zheng-yu, Chen, Yan, Zheng, Hong-mei, Lin, Mei-lan, Ou-yang, Shi, Liu, Guo-long, Zhang, Jie-wen, Shao, Feng-min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295287/
https://www.ncbi.nlm.nih.gov/pubmed/34290231
http://dx.doi.org/10.1038/s41419-021-04000-3