Cargando…

Genome-wide CRISPR/Cas9 screening identifies CARHSP1 responsible for radiation resistance in glioblastoma

Glioblastomas (GBM) is the most common primary malignant brain tumor, and radiotherapy plays a critical role in its therapeutic management. Unfortunately, the development of radioresistance is universal. Here, we identified calcium-regulated heat-stable protein 1 (CARHSP1) as a critical driver for r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Guo-dong, Yu, Jing, Sun, Zheng-yu, Chen, Yan, Zheng, Hong-mei, Lin, Mei-lan, Ou-yang, Shi, Liu, Guo-long, Zhang, Jie-wen, Shao, Feng-min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295287/ https://www.ncbi.nlm.nih.gov/pubmed/34290231 http://dx.doi.org/10.1038/s41419-021-04000-3

Ejemplares similares

Genome-wide CRISPR/Cas9 screening identifies a targetable MEST-PURA interaction in cancer metastasis
por: Xu, Wen Wen, et al.
Publicado: (2023)

Genome-Wide CRISPR-Cas9 Screen Identifies SMCHD1 as a Restriction Factor for Herpesviruses
por: Tian, Xuezhang, et al.
Publicado: (2023)

CRISPR-Cas9 identifies growth-related subtypes of glioblastoma with therapeutical significance through cell line knockdown
por: Zhao, Nannan, et al.
Publicado: (2023)

CRISPR/Cas9-based genome-wide screening of Dictyostelium
por: Ogasawara, Takanori, et al.
Publicado: (2022)

Genome-wide CRISPR-Cas9 screens identify mechanisms of BET bromodomain inhibitor sensitivity
por: Estoppey, David, et al.
Publicado: (2021)

Targeted genomic CRISPR-Cas9 screen identifies MAP4K4 as essential for glioblastoma invasion
por: Prolo, Laura M., et al.
Publicado: (2019)

The application of genome-wide CRISPR-Cas9 screens to dissect the molecular mechanisms of toxins
por: Wang, Bei, et al.
Publicado: (2022)

CRISPR/Cas9 screening using unique molecular identifiers
por: Schmierer, Bernhard, et al.
Publicado: (2017)

Applications and explorations of CRISPR/Cas9 in CAR T-cell therapy
por: Li, Chenggong, et al.
Publicado: (2020)

Genome-wide CRISPR/Cas9 Screen Identifies Host Factors Essential for Influenza Virus Replication
por: Han, Julianna, et al.
Publicado: (2018)

Genome-wide CRISPR/Cas9 screening identifies determinant of panobinostat sensitivity in acute lymphoblastic leukemia
por: Jiang, Chuang, et al.
Publicado: (2022)

Genome wide CRISPR/Cas9 screen identifies the coagulation factor IX (F9) as a regulator of senescence
por: Carpintero-Fernández, Paula, et al.
Publicado: (2022)

DUSP2 deletion with CRISPR/Cas9 promotes Mauthner cell axonal regeneration at the early stage of zebrafish
por: Shao, Guo-Jian, et al.
Publicado: (2022)

Genome-wide CRISPR-cas9 knockout screening identifies GRB7 as a driver for MEK inhibitor resistance in KRAS mutant colon cancer
por: Yu, Chune, et al.
Publicado: (2021)

CRISPR/Cas9 genome-wide screening identifies KEAP1 as a sorafenib, lenvatinib, and regorafenib sensitivity gene in hepatocellular carcinoma
por: Zheng, Adi, et al.
Publicado: (2019)

Genome-wide CRISPR/Cas9 library screen identifies PCMT1 as a critical driver of ovarian cancer metastasis
por: Zhang, Jingjing, et al.
Publicado: (2022)

Applications of CRISPR-Cas9 Technology to Genome Editing in Glioblastoma Multiforme
por: Al-Sammarraie, Nadia, et al.
Publicado: (2021)

Analysis of CRISPR‐Cas9 screens identifies genetic dependencies in melanoma
por: Christodoulou, Eirini, et al.
Publicado: (2020)

Genome-Wide CRISPR-Cas9 Screen Identifies MicroRNAs That Regulate Myeloid Leukemia Cell Growth
por: Wallace, Jared, et al.
Publicado: (2016)

A genome-wide CRISPR/Cas9 screen to identify phagocytosis modulators in monocytic THP-1 cells
por: Lindner, Benjamin, et al.
Publicado: (2021)

P1228: GENOME-WIDE CRISPR-CAS9 SCREENING IDENTIFIES THERAPEUTIC TARGETS FOR MATURE T-CELL MALIGNANCIES
por: Timonen, Sanna, et al.
Publicado: (2023)

Genome-Wide CRISPR/Cas9 Screen Identifies New Genes Critical for Defense Against Oxidant Stress in Toxoplasma gondii
por: Chen, Yun, et al.
Publicado: (2021)

Efficient inhibition of duck hepatitis B virus DNA by the CRISPR/Cas9 system
por: Zheng, Qingfen, et al.
Publicado: (2017)

Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens
por: Hart, Traver, et al.
Publicado: (2017)

Genome‐Wide CRISPR‐Cas9 Screening Identifies NF‐κB/E2F6 Responsible for EGFRvIII‐Associated Temozolomide Resistance in Glioblastoma
por: Huang, Kai, et al.
Publicado: (2019)

Minimal genome-wide human CRISPR-Cas9 library
por: Gonçalves, Emanuel, et al.
Publicado: (2021)

Genome-wide CRISPR-Cas9 screening identifies that hypoxia-inducible factor-1a-induced CBX8 transcription promotes pancreatic cancer progression via IRS1/AKT axis
por: Teng, Bu-Wei, et al.
Publicado: (2021)

High-fidelity CRISPR-Cas9 variants with undetectable genome-wide off-targets
por: Kleinstiver, Benjamin P., et al.
Publicado: (2016)

Genome-wide CRISPR-dCas9 screens in E. coli identify essential genes and phage host factors
por: Rousset, François, et al.
Publicado: (2018)

Genome-wide CRISPR/Cas9 library screening identified PHGDH as a critical driver for Sorafenib resistance in HCC
por: Wei, Lai, et al.
Publicado: (2019)

Transgelin: a new gene involved in LDL endocytosis identified by a genome-wide CRISPR-Cas9 screen
por: Lucero, Diego, et al.
Publicado: (2021)

Genome-wide CRISPR/Cas9 screen identifies etoposide response modulators associated with clinical outcomes in pediatric AML
por: Nguyen, Nam H. K., et al.
Publicado: (2022)

Genome-wide CRISPR-Cas9 screen analyzed by SLIDER identifies network of repressor complexes that regulate TRIM24
por: Patel, Lalit R., et al.
Publicado: (2023)

Systematic screening for potential therapeutic targets in osteosarcoma through a kinome-wide CRISPR-Cas9 library
por: Wu, Yuanzhong, et al.
Publicado: (2020)

Engineered Extracellular Vesicle-Delivered CRISPR/Cas9 for Radiotherapy Sensitization of Glioblastoma
por: Liu, Xiao, et al.
Publicado: (2023)

A CRISPR/Cas9 Functional Screen Identifies Rare Tumor Suppressors
por: Katigbak, Alexandra, et al.
Publicado: (2016)

Correction to “Genome-wide CRISPR-Cas9 screening identifies that hypoxia-inducible factor-1a-induced CBX8 transcription promotes pancreatic cancer progression via IRS1/AKT axis”
por: Teng, Bu-Wei, et al.
Publicado: (2022)

Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening
por: Kiessling, Michael K., et al.
Publicado: (2016)

Crispr Library Screening: Genome‐Wide CRISPR‐Cas9 Screening Identifies NF‐κB/E2F6 Responsible for EGFRvIII‐Associated Temozolomide Resistance in Glioblastoma (Adv. Sci. 17/2019)
por: Huang, Kai, et al.
Publicado: (2019)

CRISPR-Cas9 screen in human embryonic stem cells to identify genes required for neural differentiation
por: Qi, Shutao, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_looa6q5jgobpnvk6gsrocm2gmr