Targeting the latent human cytomegalovirus reservoir for T-cell-mediated killing with virus-specific nanobodies

Latent human cytomegalovirus (HCMV) infection is characterized by limited gene expression, making latent HCMV infections refractory to current treatments targeting viral replication. However, reactivation of latent HCMV in immunosuppressed solid organ and stem cell transplant patients often results...

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Detalles Bibliográficos
Autores principales: De Groof, Timo W. M., Elder, Elizabeth G., Lim, Eleanor Y., Heukers, Raimond, Bergkamp, Nick D., Groves, Ian J., Wills, Mark, Sinclair, John H., Smit, Martine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295288/
https://www.ncbi.nlm.nih.gov/pubmed/34290252
http://dx.doi.org/10.1038/s41467-021-24608-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295288/
https://www.ncbi.nlm.nih.gov/pubmed/34290252
http://dx.doi.org/10.1038/s41467-021-24608-5

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