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Genetic association studies of alterations in protein function expose recessive effects on cancer predisposition

The characterization of germline genetic variation affecting cancer risk, known as cancer predisposition, is fundamental to preventive and personalized medicine. Studies of genetic cancer predisposition typically identify significant genomic regions based on family-based cohorts or genome-wide assoc...

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Detalles Bibliográficos
Autores principales: Brandes, Nadav, Linial, Nathan, Linial, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295298/
https://www.ncbi.nlm.nih.gov/pubmed/34290314
http://dx.doi.org/10.1038/s41598-021-94252-y