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Genetic association studies of alterations in protein function expose recessive effects on cancer predisposition
The characterization of germline genetic variation affecting cancer risk, known as cancer predisposition, is fundamental to preventive and personalized medicine. Studies of genetic cancer predisposition typically identify significant genomic regions based on family-based cohorts or genome-wide assoc...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295298/ https://www.ncbi.nlm.nih.gov/pubmed/34290314 http://dx.doi.org/10.1038/s41598-021-94252-y |