Cargando…

Genome-wide chromatin accessibility analyses provide a map for enhancing optic nerve regeneration

Retinal Ganglion Cells (RGCs) lose their ability to grow axons during development. Adult RGCs thus fail to regenerate their axons after injury, leading to vision loss. To uncover mechanisms that promote regeneration of RGC axons, we identified transcription factors (TF) and open chromatin regions th...

Descripción completa

Detalles Bibliográficos
Autores principales: Pita-Thomas, Wolfgang, Gonçalves, Tassia Mangetti, Kumar, Ajeet, Zhao, Guoyan, Cavalli, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295311/
https://www.ncbi.nlm.nih.gov/pubmed/34290335
http://dx.doi.org/10.1038/s41598-021-94341-y