Targeted delivery of cytotoxic proteins to prostate cancer via conjugation to small molecule urea-based PSMA inhibitors

Prostate cancer cells are characterized by a remarkably low proliferative rate and the production of high levels of prostate-specific proteases. Protein-based toxins are attractive candidates for prostate cancer therapy because they kill cells via proliferation-independent mechanisms. However, the n...

Descripción completa

Detalles Bibliográficos
Autores principales: Rogers, O. C., Rosen, D. M., Antony, L., Harper, H. M., Das, D., Yang, X., Minn, I., Mease, R. C., Pomper, M. G., Denmeade, S. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295317/
https://www.ncbi.nlm.nih.gov/pubmed/34290365
http://dx.doi.org/10.1038/s41598-021-94534-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295317/
https://www.ncbi.nlm.nih.gov/pubmed/34290365
http://dx.doi.org/10.1038/s41598-021-94534-5

Ejemplares similares