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Targeted delivery of cytotoxic proteins to prostate cancer via conjugation to small molecule urea-based PSMA inhibitors

Prostate cancer cells are characterized by a remarkably low proliferative rate and the production of high levels of prostate-specific proteases. Protein-based toxins are attractive candidates for prostate cancer therapy because they kill cells via proliferation-independent mechanisms. However, the n...

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Detalles Bibliográficos
Autores principales:	Rogers, O. C., Rosen, D. M., Antony, L., Harper, H. M., Das, D., Yang, X., Minn, I., Mease, R. C., Pomper, M. G., Denmeade, S. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295317/ https://www.ncbi.nlm.nih.gov/pubmed/34290365 http://dx.doi.org/10.1038/s41598-021-94534-5

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