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Pazopanib for severe bleeding and transfusion-dependent anemia in hereditary hemorrhagic telangiectasia

Hereditary hemorrhagic telangiectasia (HHT) is a rare angiogenic disorder causing chronic gastrointestinal bleeding, epistaxis, and severe anemia. Pazopanib is an oral multi-kinase angiogenesis inhibitor with promise to treat bleeding in HHT. We analyzed outcomes of HHT patients with the most severe...

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Detalles Bibliográficos
Autores principales: Parambil, Joseph G., Gossage, James R., McCrae, Keith R., Woodard, Troy D., Menon, K. V. Narayanan, Timmerman, Kasi L., Pederson, Douglas P., Sprecher, Dennis L., Al-Samkari, Hanny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8295629/
https://www.ncbi.nlm.nih.gov/pubmed/34292451
http://dx.doi.org/10.1007/s10456-021-09807-4